🧪 As a complement to CCT251545 and CCT251921, the study also highlights MSC2530818 as a valuable orthogonal CDK8/19 probe, further strengthening confidence in on-target effects and enabling robust mechanistic studies.
#ChemicalProbes #CDK8 #TargetValidation
📣 Happening today!
Join the Babraham Distinguished Lecture with Prof Paul Workman | 1–2pm, 12 June
🧬 “Probing and drugging stress pathways: Chemical Biology and therapeutic discovery”
#Cancer#StressResponse#DrugDiscovery#ChemicalBiology #TargetValidation#MolecularPharmacology
Next week we welcome leading cancer research scientist Prof Paul Workman to Campus for the latest in the Babraham Distinguished Lecture series.
�ow.ly/fY7F50VYQp38x
3️⃣ How Are Drug Targets Identified?
Target discovery often starts at the molecular level.
🔍 Key approaches:
🔹 Gene expression profiling
🔹 RNAi and CRISPR screening
🔹 Proteomics & phosphoproteomics
🧪 These tools reveal who to drug—and how.👇
#TargetValidation
Need a robust highly sensitive #WesternBlot assay for your preclinical studies or clinical trials? Champions' advanced Western Blot assay was developed for #TargetValidation, sample characterization, detecting post-translational modifications, and more. hubs.li/Q02_FTWz0