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Yuelian Sun
Yuelian Sun @JuliaYS8 ·
Our new research in @JNNP_BMJ: Does #FolicAcid reduce birth defects risk for women on #ASM? Our #TargetTrial emulation shows timing is everything. ✅ 1-12 weeks PRE-conception: 45% risk reduction. ❌ Post-conception: No significant effect . Direct link to our findings: [Link]
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Chelsea Messinger, MD, PhD
Chelsea Messinger, MD, PhD @chelsmessinger ·
Replying to @chelsmessinger
🧵9/ In addition, we describe unique aspects of this study from a causal inference perspective using the #targettrial framework, including challenges of studying obstetric interventions that can occur both pre- and post-conceptionally in both observational and randomized studies.C
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CAUSALab
CAUSALab @CAUSALab ·
Last chance to register! Next week in Barcelona: Towards Regulatory-Grade Causal Inference from Observational Data applies practical #targettrial use cases for regulatory & research purposes. 📅 Mar 24-25, 2025 📍 Barcelona, Spain Learn more & registerrtihs.org/updates-and-ev…UCx
Towards Regulatory-Grade Causal Inference from Observational Data (March 24-25, 2025)
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CAUSALab
CAUSALab @CAUSALab ·
🌐 Upcoming course collaboration w/@RTIHS Towards Regulatory-Grade Causal Inference from Observational Data applies practical #targettrial use cases for regulatory & research purposes. 📅 Mar 24-25, 2025 📍 Barcelona, Spain Register to attenrtihs.org/updates-and-ev…pQ2A
Towards Regulatory-Grade Causal Inference from Observational Data (March 24-25, 2025)
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Miguel Hernán
Miguel Hernán @_MiguelHernan ·
Replying to @_MiguelHernan
2/ Immortal time may occur when individuals are 1) assigned to treatment strategies based on post-eligibility information or 2) determined to be eligible based on post-assignment information #TargetTrial emulation prevents it by synchronizing eligibility and assignment at time 0
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