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Read-Across does not fail because uncertainty exists. It fails when uncertainty is poorly characterised.
Learn more >> bluefrogscientific.com/chemical-regul…
#ReadAcross #ReadAcrossStrategy #REACH #EUREACH #REACHRegulation #REACHRegistration #Toxicology #OECD #EFSA #ECHA #DataGap #CLP
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March 2 is Read Across America Day! #readacrossamerica
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🔬 New study (Mizuno et al., 2026) combining alvaDesc molecular descriptors with mechanism-based in vitro assays to improve read-across prediction of rat thyroid carcinogenicity.
�doi.org/10.1016/j.fct.…Wc
🔗 alvaDesalvascience.com/alvadesc/g2o
#alvaDesc #ReadAcross #QSAR #NAqL2
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New study by Samanta et al. shows how q-RASAR + QSAR can predict terminal half-life (t½) for 895 drugs doi.org/10.1007/s11030… using 2D descriptors from #alvaDesc.
🔗 Learn more about alvaDesc:alvascience.com/alvadesc/o
#QSAR #ReadAcross #Pharmacokinetics #DrugDiscoveryY
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Improving Read-Across Acceptance Under REACH - Lessons from Surfactants.
Why many read-across submissions under REACH fail to gain acceptance by authorities...
Learn more >> bluefrogscientific.com/chemical-regul…
#ReadAcross #REACH #REACHCompliance #ECHA #NAMs #ChemicalCompliance
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We have developed machine learning (ML) models to accurately classify the DICTrank dataset of the US-FDA.
The Open Access article is available from doi.org/10.1016/j.insi…
Research supported by the @ICMRDELHI
#qsar #readacross #Chemometrics #Cheminformatics #compchem
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🔬 New study uses alvaDesc + in vitro data to predict nongenotoxic carcinogenicity of pesticides via read-across.
Balanced accuracy up to 0.82 for rat tumor endpoints.doi.org/10.1016/j.fct.…q
Check alvaDesc at:alvascience.com/alvadesc/o
#QSAR #Toxicology #ReadAcross #NAMsb
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DTC Laboratory, #JadavpurUniversity presentations in QSAR2025 Workshop at @MarioNegriIRCCS , Milan, Italy
qsar2025.marionegri.it/program.html
#QSAR #Readacross #Cheminformatics #Chemometrics #qRASAR #ARKA #machinelearning
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15 Years of Read-Across Under EU REACH – Lessons from ECHA’s Testing Proposal & Compliance Check Decisions.
Valuable resource for anyone planning to use read-across in future REACH submissions.
Read more >> bluefrogscientific.com/chemical-regul…
#ReadAcross #ECHA #REACH #ChemicalRegulation
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It's about TO ACCEPT or NOT ACCEPT #Readacross! @tamusuperfund Dr. Ivan Rusyn shared results from a #systematicreview & participated on the active panel discussion. @NIH_NIEHS #NIEHS_SRP @tamutox @tamuvetmed
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