PROTACs improve selectivity for targeted proteins scienceopen.com/hosted-documen… #PROTAC #ProteinSelectivity #TargetedDegradation #DrugDesign #ChemicalBiology

Mutations in TF MAX enhance DNA selectivity by changing folding and binding, as shown in studies with >1700 Kd measurements and >500 rate constants. #ProteinSelectivity PMID:39805837, Nat Commun 2025, @NatureComms doi.org/10.1038/s41467…